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Targeted Removal of Senescent Cells in Adipose Tissue Improves Type 2 Diabetes
Nearly half of all adults in the U.S. are considered obese, and the incidence of obesity has steadily risen over time in nearly every...
Dec 16, 2021


Fasting: The Critical Component of Calorie Restriction
In 1935 Clive McCay published a paper demonstrating the pro-longevity effects of caloric restriction that would come to shape the future...
Nov 8, 2021


5-Minute Daily Breathing Therapy as Effective in Reducing High Blood Pressure and Risk of Cardiovasc
In the United States, more than 65% of individuals above the age of 50 have hypertension (abnormally high blood pressure). The occurrence...
Oct 25, 2021


Parasite Affords Extreme Lifespan to Ants
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Oct 18, 2021
Association of dietary sulfur amino acid intake with mortality from diabetes and other causes
#diabetes #mortality #Dong #SAAR #sulfuraminoacids
Oct 11, 2021


Webinar for Aging Science Talks Chaired by Dr. Nichenametla
OFAS Associate Scientist Dr. Sailendra Nichenametla will chair a webinar, “Sulfur Amino Acid Restriction – Moving from Animals to...
Oct 1, 2021
Sulfur Amino Acid-Restricted Diets: Mechanisms and Health Benefits
#Ables #agingresearch #sulfuraminoacids
Sep 23, 2021
Dr. Norman Orentreich Award for Young Investigator on Aging Presented to Cristal Hill
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Sep 18, 2021
Can exercise prevent “inflamm-aging”?
Researchers from Mayo Clinic have uncovered a novel way in which exercise may contribute to healthy aging by suppressing an age-related...
Aug 16, 2021
Post-Doctoral Research Position Available
A post-doctoral position at the Orentreich Foundation for the Advancement of Science (Cold Spring-on-Hudson, NY) is immediately available...
Jul 6, 2021
Selenium supplementation inhibits IGF-1 signaling and confers methionine restriction-like healthspan
#agingresearch #Johnson #sulfuraminoacids
Mar 30, 2021
Selenium supplementation protects against obesity and may extend lifespan
Adding the nutrient selenium to diets protects against obesity and provides metabolic benefits to mice, according to a study published...
Mar 30, 2021


2020 OFAS Report of Directors
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Feb 3, 2021
Differential effects of sulfur amino acid-restricted and low-calorie diets on gut microbiome profile
#agingresearch #Nichenametla #sulfuraminoacids
Jan 1, 2021
Age-at-onset-dependent effects of sulfur amino acid restriction on markers of growth and stress in m
#agingresearch #Nichenametla #sulfuraminoacids
Jul 13, 2020
Weight Loss and Concomitant Adipose Autophagy in Methionine-Restricted Obese Mice is Not Dependent o
Methionine restriction (MR) prevents obesity because of a futile lipid cycle in which two metabolic pathways run simultaneously in...
May 6, 2020
Weight loss and concomitant adipose autophagy in methionine-restricted obese mice is not dependent o
#Ables #methioninerestriction #Nichenametla #obesity
May 4, 2020
Association of sulfur amino acid consumption with cardiometabolic risk factors: Cross-sectional find
#diabetes #Cardiometabolicdiseases #methionine #Dong #SAAR #sulfuraminoacids #cysteine
Feb 3, 2020
Methionine restriction delays aging-related urogenital diseases in male Fischer 344 rats
Despina Komninou, Virginia L. Malloy, Jay A. Zimmerman, Raghu Sinha, John P. Richie Jr. GeroScience. 2020 Feb PMID: 31728897 Dietary...
Dec 23, 2019
Extension of cellular lifespan by methionine restriction involves alterations in central carbon meta
#Johnson #lifespan #methioninerestriction
Nov 6, 2019
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