PUBLICATIONS
The following list shows scientific publications in reverse date order. Open-access publications are indicated by the citation shown in red. Links to PubMed records for others can be accessed by clicking on the PMID.
2024
Interindividual differences of dietary fat-inducible Mest in white adipose tissue of C57BL/6J mice are not heritable.
Anunciado-Koza RVP, Yin H, Bilodeau CL, Cooke D, Ables GP, Ryzhov S, Koza RA.
Obesity (Silver Spring). 2024 Apr 14. doi: 10.1002/oby.24020. Online ahead of print. | PMID:38616328
2024
An antireductant approach ameliorates misfolded proinsulin-induced hyperglycemia and glucose intolerance in male Akita mice.
Mattocks DAL, Ommi NB, Malloy VL, Nichenametla SN.
Geroscience. 2024 Sep 19. doi: 10.1007/s11357-024-01326-6 | PMID: 39294474
2024
Intermittent methionine restriction reduces marrow fat accumulation and preserves more bone mass than continuous methionine restriction
Johnson JE, Horowitz, MC, Plummer JP
Aging Biology, 2024; 2: 20230019 | PMID: 38550776
2023
Physical activity of mice on dietary sulfur amino acid restriction is influenced by age of diet initiation and biological sex
Cooke D, Ables GP
Scientific Reports, 2023; 13(1): 20609 | PMID: 37996548
2023
Cystine rather than cysteine is the preferred substrate for β-elimination by cystathionine γ-lyase: implications for dietary methionine restriction
Jeitner TM, Azcona JA, Ables GP, Cooke D, Horowitz MC, Singh P, Kelly JM, Cooper AJL
Geroscience, 2023; : | PMID: 37217633
2023
Dietary Methionine and Total Sulfur Amino Acid Restriction in Healthy Adults
Richie Jr JP, Sinha R, Dong Z, Nichenametla SN, Ables GP, Ciccarella A, Sinha I, Calcagnotto AM, Chinchilli VM, Reinhart L, Orentreich D
The Journal of Nutrition, Health & Aging, 2023; 27(2): 111-123 | PMID: 36806866
2023
Effects of dietary methionine restriction on age-related changes in perivascular and beiging adipose tissues in the mouse
M McGilvrey, Fortier B, Tero B, Cooke D, Cooper E, Walker J, Koza R, Ables G, Liaw L
Obesity (Silver Spring), 2023; 31(1): 159-170 | PMID: 36513498
2022
Cysteine restriction-specific effects of sulfur amino acid restriction on lipid metabolism
Nichenametla SN, Mattocks DAL, Cooke D, Midya V, Malloy VL, Mansilla W, Øvrebø B, Turner C, Bastani NE, Sokolová J, Pavlíková M, Richie JP, Shoveller AK, Refsum H, Olsen T, Vinknes KJ, Kožich V, Ables GP
Aging Cell, 2022; 21(12): e13739 | PMID: 36403077
2022
Cumulative consumption of sulfur amino acids and risk of diabetes: a prospective cohort study
Dong Z, Richie JP, Gao X, Al-Shaar L, Nichenametla SN, Shen B, Orentreich D
Journal of Nutrition, 2022; 152(11): 2419 | PMID: 35945644
2022
Intermittent methionine restriction reduces IGF-1 levels and produces similar healthspan benefits to continuous methionine restriction
Plummer JD, Johnson JE
Aging Cell, 2022; 21: e13629 | PMID: 35570387
2021
ISulfur Amino Acid-Restricted Diets: Mechanisms and Health Benefits
Ables GP
Encyclopedia of Biological Chemistry III (Third Edition), 2021; : 105-13
2021
Selenium supplementation inhibits IGF-1 signaling and confers methionine restriction-like healthspan benefits to mice
Plummer JD, Postnikoff SDL, Tyler JK, Johnson JE
ELife, 2021; 10: e62483 | PMID: 33783357
2021
Differential effects of sulfur amino acid-restricted and low-calorie diets on gut microbiome profile and bile acid composition in male C57BL6/J mice
Nichenametla SN, Mattocks DAL, Midya V, Shneyder J
The Journals of Gerontology: Series A, 2021; 76(11) : 1922-29 | PMID: 33106871
2020
Age-at-onset-dependent effects of sulfur amino acid restriction on markers of growth and stress in male F344 rats
Nichenametla SN, Mattocks DAL, Malloy VL
Aging Cell, 2020; 19(7) : e13177 | PMID: 32573078
2020
Weight loss and concomitant adipose autophagy in methionine-restricted obese mice is not dependent on adiponectin or FGF21
Cooke D, Mattocks DAL, Nichenametla SN, Anunciado-Koza RP, Koza RA, Ables GP
Obesity, 2020; 28(6) : 1075-1085 | PMID: 32348021
2020
Methionine restriction delays aging-related urogenital diseases in male Fischer 344 rats
Komninou D, Malloy VL, Zimmerman JA, Sinha R, Richie JP
2019
Extension of cellular lifespan by methionine restriction involves alterations in central carbon metabolism and is mitophagy-dependent
Plummer JD, Johnson JE
Frontiers in Cell and Developmental Biology, 2019; 7(301) : | PMID: 31850341
2019
Dietary methionine influences therapy in mouse cancer models and alters human metabolism.
Gao X, Sanderson SM, Dai Z, Reid MA, Cooper DE, Lu M, Richie JP Jr, Ciccarella A, Calcagnotto A, Mikhael PG, Mentch SJ, Liu J, Ables G, Kirsch DG, Hsu DS, Nichenametla SN, Locasale JW
2019
Bone marrow adiposity: basic and clinical implications
Sebo ZL, Rendina-Ruedy E, Ables GP, Lindskog DM, Rodeheffer MS, Fazeli PK, Horowitz MC
2019
Identification and application of gene expression signatures associated with lifespan extension
Tyshkovskiy A, Bozaykut P, Borodinova AA, Gerashchenko MV, Ables GP, Garratt M, Khaitovich P, Clish CB, Miller RA, Gladyshev VN.
2018
Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width
Dai Z, Mentch SJ, Gao X, Nichenametla SN, Locasale JW
2018
Disease prevention and delayed aging by dietary sulfur amino acid restriction: translational implications
Dong Z, Sinha R, Richie JR
Annals of the New York Academy of Sciences, 2018; 1418: 44-55 | PMID: 29399808
2018
The role of autophagy in the regulation of yeast life span
Tyler JK, Johnson JE
Annals of the New York Academy of Sciences, 2018; 1418(1) : 31-43 | PMID: 29363766
2017
Bone marrow adipocytes.
Horowitz MC, Berry R, Holtrup B, Sebo Z, Nelson T, Fretz JA, Lindskog D, Kaplan JL, Ables GP, Rodeheffer MS, Rosen CJ.
2017
The integrated stress response in budding yeast lifespan extension
Postnikoff SDL, Johnson JE, Tyler JK
Microbial Cell (Graz, Austria), 2017; 4(11) : 368-375 | PMID: 29167799
2017
Dietary methionine restriction modulates renal response and attenuates kidney injury in mice
Cooke D, Ouattara A, Ables GP
2017
Pleiotropic responses to methionine restriction
Ables GP, Johnson JE
Experimental Gerontology, 2017; (94) : 83-88 | PMID: 28108330
2017
Short term methionine restriction increases hepatic global DNA methylation in adult but not young male C57BL/6J mice
Mattocks DA, Mentch SJ, Shneyder J, Ables GP, Sun D, Richie JP Jr, Locasale JW, Nichenametla SN
2016
Methionine-restricted diet increases miRNAs that can target RUNX2 expression and alters bone structure in young mice
Plummer J, Park M, Perodin F, Horowitz MC, Hens JR
Journal of Cellular Biochemistry, 2016; 118(1) : 31-42 | PMID: 27191548
2016
Methionine restriction alters bone morphology and affects osteoblast differentiation
Ouattara A, Cooke D, Gopalakrishnan R, Huang TH, Ables GP
Bone Reports, 2016; 5: 33-42 | PMID: 28326345
2016
Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice
Hens JR, Sinha I, Perodin F, Cooper T, Sinha R, Plummer J, Perrone CE, Orentreich D
2016
Methionine restriction beyond life-span extension
Ables GP, Hens JR, Nichenametla SN
Annals of the New York Academy of Sciences, 2016; 1363(1) : 68-79 | PMID: 26916321
2016
Dietary restrictions, bone density, and bone quality
Huang TH, Ables GP
Annals of the New York Academy of Sciences, 2016; 1363(1) : 26-39 | PMID: 26881697
2015
Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism
Mentch SJ, Mehrmohamadi M, Huang L, Liu X, Gupta D, Mattocks D, Gόmez Padilla P, Ables G, Bamman MM, Thalacker-Mercer AE, Nichenametla SN, Locasale JW
2015
Effects of methionine restriction and endurance exercise on bones of ovariectomized rats: a study of histomorphometry, densitometry, and biomechanical properties
Huang TH, Su IH, Lewis JL, Chang MS, Hsu AT, Perrone CE, Ables GP
Journal of Applied Physiology (Bethesda, Md. : 1985), 2015; 119(5) : 517-26 | PMID: 26159761
2015
Dietary methionine restriction in mice elicits an adaptive cardiovascular response to hyperhomocysteinemia
Ables GP, Ouattara A, Hampton TG, Cooke D, Perodin F, Augie I, Orentreich DS