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How Mindfulness Protects You as You Get Older
In our minds, old age is often associated with negative outcomes, such as a decline in physical health, but research consistently finds...
Apr 11, 2018


Researchers Find Reversible Cause of Vascular Aging
The hallmarks of aging in skeletal muscle include endothelial cell dysfunction, impaired microcapillary formation, and a progressive...
Apr 10, 2018


Can Drugs Delay the Onset of Age-Related Diseases?
[et_pb_section][et_pb_row][et_pb_column type=”4_4″][et_pb_text] Over the past ten years, understanding of the physiological changes that...
Feb 20, 2018


Sulfur amino acid restriction–induced changes in redox-sensitive proteins are associated with slow p
Optimal maintenance of protein quality is critical for proper cellular functions. Protein turnover (PT) is a critical contributor to...
Feb 16, 2018


The role of autophagy in the regulation of yeast life span
Aging is a complex, multifactorial process that is driven by the progressive accumulation of several types of cellular damage. Functional...
Feb 8, 2018


2017 OFAS Report of Directors
[et_pb_section admin_label=”section”] [et_pb_row admin_label=”row”] [et_pb_column type=”4_4″] [et_pb_text admin_label=”Text”] As we...
Jan 15, 2018


The integrated stress response in budding yeast lifespan extension
The ultimate goal of aging research is to develop therapeutic means to extend human lifespan, while reducing susceptibility to many...
Dec 11, 2017


MR Reduces the Effects of Kidney Injury
Did you know that kidney disease is one of the major causes of early mortality, morbidity, and rising medical costs in the United States?...
Dec 5, 2017


High Fat Diet Improves Healthspan and Memory
A recent study has demonstrated that a ketogenic diet significantly improved memory in aging mice and increased the animal’s chances of...
Sep 22, 2017


High Fat Diet Extends Longevity and Healthspan
As more people age well past their 70s, researchers have increasingly explored the issues of health and quality of life during aging. A...
Sep 22, 2017


Cellular Rejunevation – One Step Closer to Understanding Human Aging
In order to delay aging, the process of aging must first be understood; that the aging of cells is what drives the aging of an organism....
Aug 18, 2017


In Review: The Many Effects of Methionine Restriction
Our work at the Orentreich Foundation for the Advancement of Science has proven that methionine restriction (MR) extends lifespan and has...
Apr 4, 2017


2016 OFAS Report of Directors
[et_pb_section admin_label=”section”] [et_pb_row admin_label=”row”] [et_pb_column type=”4_4″] [et_pb_text admin_label=”Text”]...
Jan 25, 2017


Improving Lifespan and Healthspan in a Disorder Causing Early Aging
A team of researchers lead by Drs. Evandro Fang and Vilhelm Bohr of the National Institute of Aging–National Institutes of Health have...
Jan 25, 2017


Preserving DNA Methylation During Aging
One of the negative aspects of aging is the decreased ability to maintain normal cellular functions, which eventually manifests as...
Jan 13, 2017


NYAS Symposium – Aging & Nutrition: Novel Approaches & Techniques
OFAS and The Sackler Institute for Nutrition Science at The New York Academy of Sciences (NYAS) joined together to present a conference...
Dec 22, 2016


Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
Cellular senescence, a stress-induced state in which cells are unable to divide, is known to prevent the proliferation of potentially...
Nov 30, 2016


Dr. Gene Ables Invited to Speak at 13th International Symposium on Neurobiology and Neuroendocrinolo
13th International Symposium on Neurobiology and Neuroendocrinology of Aging July 17-22, 2016, Bregenz, Austria In keeping with our...
Jul 22, 2016


Welcome to Healthspan!
Fifty-five years ago, when my father Dr. Norman Orentreich founded OFAS, his research focused on wound healing and aging studies. Over...
Jul 21, 2016


Upcoming Symposium: Aging and Nutrition: Novel Approaches and Techniques
Several interventions have been identified that significantly extend healthy lifespan in mammals. Caloric restriction, for example, has...
Feb 15, 2016
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