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Most of us give little thought to our bones unless a problem arises—broken arms, arthritis, or similar ailments. We know that that bone health becomes increasingly important later in life and seek to prevent or delay the onset of osteoporosis, viewing the disease as one that affects only the very old. Few of us realize that the slow, steady changes leading to osteoporosis begin much earlier, shortly after puberty, and quietly progress for decades before manifesting as bone di

Methionine restriction (MR) has been known for decades to extend lifespan across multiple organisms, dating back to the seminal publication Low Methionine Ingestion by Rats Extends Life Span (N. Orentreich et al). Unlike other pro-longevity interventions—such as calorie restriction, intermittent fasting, or ketogenic diets—MR has yet to gain traction among health-conscious individuals. This is largely due to the overabundance of methionine in most dietary protein sources, mak

By delving into the mechanisms that drive and are driven by low-level inflammation, a new study reveals potential pathways for developing an