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Dietary methionine influences therapy in mouse cancer models and alters human metabolism.
Gao X, Sanderson SM, Dai Z, Reid MA, Cooper DE, Lu M, Richie JP Jr, Ciccarella A, Calcagnotto A, Mikhael PG, Mentch SJ, Liu J, Ables G,...
Oct 17, 2019
Bone marrow adiposity: basic and clinical implications
Sebo ZL, Rendina-Ruedy E, Ables GP, Lindskog DM, Rodeheffer MS, Fazeli PK, Horowitz MC. Endocr Rev. 2019 Oct 1;40(5):1187-1206 PMID:...
Oct 17, 2019
Identification and application of gene expression signatures associated with lifespan extension
Tyshkovskiy A, Bozaykut P, Borodinova AA, Gerashchenko MV, Ables GP, Garratt M, Khaitovich P, Clish CB, Miller RA, Gladyshev VN. Cell...
Oct 17, 2019
The dietary switch that may boost longevity and its correlation to SAAR
A new epidemiological study published in The BMJ explores the association between eating red meat and the risk of death, specifically how...
Jun 26, 2019


In Memoriam Norman Orentreich, MD
Dr. Norman Orentreich 1922-2019 It is with profound sadness that we announce the recent passing of our Founder and Co-Director, Dr....
Apr 26, 2019


The EAT–Lancet Commission on Diet, Healthspan, and Sustainability
Human health, diet, and environmental sustainability are prevailing concerns that share many common uncertainties. Fulfilling the...
Feb 13, 2019


2018 OFAS Report of Directors
[et_pb_section bb_built=”1″][et_pb_row][et_pb_column type=”4_4″][et_pb_text] As we begin the new year, we at the Orentreich Foundation...
Jan 30, 2019


OFAS Successfully Hosted AGA Session
This year, OFAS hosted a pre-meeting session at the AGE 47th Annual Meeting in Philadelphia. The theme of the conference was “Improving...
Aug 2, 2018


Analysis of environmental data strengthens the case for plant-based diets
Researchers at Oxford University and the Swiss agricultural research institute, Agroscope, have created the most comprehensive database...
Jun 12, 2018


OFAS Hosting Session at AGE 47th Annual Meeting
For years, Orentreich Foundation for the Advancement of Science has researched biomedical interventions to prevent, halt, or reverse...
Jun 1, 2018
Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width
[et_pb_section bb_built=”1″ _builder_version=”3.0.47″][et_pb_row _builder_version=”3.0.47″ background_size=”initial”...
May 15, 2018


OFAS Will Lead Their First Jane’s Walk
The Orentreich Foundation for the Advancement of Science is excited to announce that we will be leading our first Jane’s Walk in New York...
Apr 20, 2018


How Mindfulness Protects You as You Get Older
In our minds, old age is often associated with negative outcomes, such as a decline in physical health, but research consistently finds...
Apr 11, 2018


Researchers Find Reversible Cause of Vascular Aging
The hallmarks of aging in skeletal muscle include endothelial cell dysfunction, impaired microcapillary formation, and a progressive...
Apr 10, 2018
Disease prevention and delayed aging by dietary sulfur amino acid restriction: translational implica
#aging #Dong #methionine #SAAR
Apr 1, 2018


Can Drugs Delay the Onset of Age-Related Diseases?
[et_pb_section][et_pb_row][et_pb_column type=”4_4″][et_pb_text] Over the past ten years, understanding of the physiological changes that...
Feb 20, 2018


Sulfur amino acid restriction–induced changes in redox-sensitive proteins are associated with slow p
Optimal maintenance of protein quality is critical for proper cellular functions. Protein turnover (PT) is a critical contributor to...
Feb 16, 2018


The role of autophagy in the regulation of yeast life span
Aging is a complex, multifactorial process that is driven by the progressive accumulation of several types of cellular damage. Functional...
Feb 8, 2018
Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow p
Nichenametla SN, Mattocks DAL, Malloy VL, Pinto JT Ann. N. Y. Acad. Sci. 2018 Jan; PMID: 29377163 The mechanisms underlying life span...
Jan 29, 2018
The role of autophagy in the regulation of yeast life span
Tyler JK, Johnson JE Ann. N. Y. Acad. Sci. 2018 Jan; PMID: 29363766 The goal of the aging field is to develop novel therapeutic...
Jan 24, 2018
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