Cystine rather than cysteine is the preferred substrate for β-elimination by cystathionine γ-lyase: implications for dietary methionine restriction
Jeitner TM, Azcona JA, Ables GP, Cooke D, Horowitz MC, Singh P, Kelly JM, Cooper AJL
Geroscience, 2023; : | PMID: 37217633

Dietary Methionine and Total Sulfur Amino Acid Restriction in Healthy Adults
Richie Jr JP, Sinha R, Dong Z, Nichenametla SN, Ables GP, Ciccarella A, Sinha I, Calcagnotto AM, Chinchilli VM, Reinhart L, Orentreich D
The Journal of Nutrition, Health & Aging, 2023; 27(2): 111-123 | PMID: 36806866

Effects of dietary methionine restriction on age-related changes in perivascular and beiging adipose tissues in the mouse
M McGilvrey, Fortier B, Tero B, Cooke D, Cooper E, Walker J, Koza R, Ables G, Liaw L
Obesity (Silver Spring), 2023; 31(1): 159-170 | PMID: 36513498

Cysteine restriction-specific effects of sulfur amino acid restriction on lipid metabolism
Nichenametla SN, Mattocks DAL, Cooke D, Midya V, Malloy VL, Mansilla W, Øvrebø B, Turner C, Bastani NE, Sokolová J, Pavlíková M, Richie JP, Shoveller AK, Refsum H, Olsen T, Vinknes KJ, Kožich V, Ables GP
Aging Cell, 2022; 21(12): e13739 | PMID: 36403077

Cumulative consumption of sulfur amino acids and risk of diabetes: a prospective cohort study
Dong Z, Richie JP, Gao X, Al-Shaar L, Nichenametla SN, Shen B, Orentreich D
Journal of Nutrition, 2022; 152(11): 2419 | PMID: 35945644

Intermittent methionine restriction reduces IGF-1 levels and produces similar healthspan benefits to continuous methionine restriction
Plummer JD, Johnson JE
Aging Cell, 2022; 21: e13629 | PMID: 35570387

Sulfur Amino Acid-Restricted Diets: Mechanisms and Health Benefits
Ables GP
Encyclopedia of Biological Chemistry III (Third Edition), 2021; : 105-13 | PMID:

Selenium supplementation inhibits IGF-1 signaling and confers methionine restriction-like healthspan benefits to mice
Plummer JD, Postnikoff SDL, Tyler JK, Johnson JE
ELife, 2021; 10: e62483 | PMID: 33783357

Differential effects of sulfur amino acid-restricted and low-calorie diets on gut microbiome profile and bile acid composition in male C57BL6/J mice
Nichenametla SN, Mattocks DAL, Midya V, Shneyder J
The Journals of Gerontology: Series A, 2021; 76(11) : 1922-29 | PMID: 33106871

Age-at-onset-dependent effects of sulfur amino acid restriction on markers of growth and stress in male F344 rats
Nichenametla SN, Mattocks DAL, Malloy VL
Aging Cell, 2020; 19(7) : e13177 | PMID: 32573078

Weight loss and concomitant adipose autophagy in methionine-restricted obese mice is not dependent on adiponectin or FGF21
Cooke D, Mattocks DAL, Nichenametla SN, Anunciado-Koza RP, Koza RA, Ables GP
Obesity, 2020; 28(6) : 1075-1085 | PMID: 32348021

Methionine restriction delays aging-related urogenital diseases in male Fischer 344 rats
Komninou D, Malloy VL, Zimmerman JA, Sinha R, Richie JP
GeroScience, 2020; 42(1) : 287-297 | PMID: 31728897

Extension of cellular lifespan by methionine restriction involves alterations in central carbon metabolism and is mitophagy-dependent
Plummer JD, Johnson JE
Frontiers in Cell and Developmental Biology, 2019; 7(301) : | PMID: 31850341

Dietary methionine influences therapy in mouse cancer models and alters human metabolism.
Gao X, Sanderson SM, Dai Z, Reid MA, Cooper DE, Lu M, Richie JP Jr, Ciccarella A, Calcagnotto A, Mikhael PG, Mentch SJ, Liu J, Ables G, Kirsch DG, Hsu DS, Nichenametla SN, Locasale JW
Nature, 2019; 572(7769) : 397-401 | PMID: 31367041

Bone marrow adiposity: basic and clinical implications
Sebo ZL, Rendina-Ruedy E, Ables GP, Lindskog DM, Rodeheffer MS, Fazeli PK, Horowitz MC
Endocrine Reviews, 2019; 40(5) : 1187-1206 | PMID: 31127816

Identification and application of gene expression signatures associated with lifespan extension
Tyshkovskiy A, Bozaykut P, Borodinova AA, Gerashchenko MV, Ables GP, Garratt M, Khaitovich P, Clish CB, Miller RA, Gladyshev VN.
Cell Metabolism, 2019; 30(3) : 573-593.e8 | PMID: 31353263 

Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width
Dai Z, Mentch SJ, Gao X, Nichenametla SN, Locasale JW
Nature Communications, 2018; 9(1) : 1955 | PMID: 29769529

Disease prevention and delayed aging by dietary sulfur amino acid restriction: translational implications
Dong Z, Sinha R, Richie JR
Annals of the New York Academy of Sciences, 2018; 1418: 44-55 | PMID: 29399808

Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow protein synthesis rates
Nichenametla SN, Mattocks DAL, Malloy VL, Pinto JT
Annals of the New York Academy of Sciences, 2018; 1418(1) : 80-94 | PMID: 29377163

The role of autophagy in the regulation of yeast life span
Tyler JK, Johnson JE
Annals of the New York Academy of Sciences, 2018; 1418(1) : 31-43 | PMID: 29363766

Bone marrow adipocytes.
Horowitz MC, Berry R, Holtrup B, Sebo Z, Nelson T, Fretz JA, Lindskog D, Kaplan JL, Ables GP, Rodeheffer MS, Rosen CJ.
Adipocytes, 2017; 6(3) : 193-204 | PMID: 28872979

The integrated stress response in budding yeast lifespan extension
Postnikoff SDL, Johnson JE, Tyler JK
Microbial Cell (Graz, Austria), 2017; 4(11) : 368-375 | PMID: 29167799

Dietary methionine restriction modulates renal response and attenuates kidney injury in mice
Cooke D, Ouattara A, Ables GP
The FASEB Journal, 2017; 32(2) : 693-702 | PMID: 28970255

Pleiotropic responses to methionine restriction
Ables GP, Johnson JE
Experimental Gerontology, 2017; (94) : 83-88 | PMID: 28108330

Short term methionine restriction increases hepatic global DNA methylation in adult but not young male C57BL/6J mice
Mattocks DA, Mentch SJ, Shneyder J, Ables GP, Sun D, Richie JP Jr, Locasale JW, Nichenametla SN
Experimental Gerontology, 2017; (88) : 1-8 | PMID: 27940170

Methionine-restricted diet increases miRNAs that can target RUNX2 expression and alters bone structure in young mice
Plummer J, Park M, Perodin F, Horowitz MC, Hens JR
Journal of Cellular Biochemistry, 2016; 118(1) : 31-42 | PMID: 27191548

Methionine restriction alters bone morphology and affects osteoblast differentiation
Ouattara A, Cooke D, Gopalakrishnan R, Huang TH, Ables GP
Bone Reports, 2016; 5: 33-42 | PMID: 28326345

Methionine restriction beyond life-span extension
Ables GP, Hens JR, Nichenametla SN
Annals of the New York Academy of Sciences, 2016; 1363(1) : 68-79 | PMID: 26916321

Dietary restrictions, bone density, and bone quality
Huang TH, Ables GP
Annals of the New York Academy of Sciences, 2016; 1363(1) : 26-39 | PMID: 26881697

Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice
Hens JR, Sinha I, Perodin F, Cooper T, Sinha R, Plummer J, Perrone CE, Orentreich D
BMC Cancer, 2016; 16(1) : 349 | PMID: 27255182

Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism
Mentch SJ, Mehrmohamadi M, Huang L, Liu X, Gupta D, Mattocks D, Gόmez Padilla P, Ables G, Bamman MM, Thalacker-Mercer AE, Nichenametla SN, Locasale JW
Cell Metabolism, 2015; 22(5) : 861-73 | PMID: 26411344

Effects of methionine restriction and endurance exercise on bones of ovariectomized rats: a study of histomorphometry, densitometry, and biomechanical properties
Huang TH, Su IH, Lewis JL, Chang MS, Hsu AT, Perrone CE, Ables GP
Journal of Applied Physiology (Bethesda, Md. : 1985), 2015; 119(5) : 517-26 | PMID: 26159761

Dietary methionine restriction in mice elicits an adaptive cardiovascular response to hyperhomocysteinemia
Ables GP, Ouattara A, Hampton TG, Cooke D, Perodin F, Augie I, Orentreich DS
Scientific Reports, 2015; 5: 8886 | PMID: 25744495

Dietary methionine restriction inhibits prostatic intraepithelial neoplasia in TRAMP mice
Sinha R, Cooper TK, Rogers CJ, Sinha I, Turbitt WJ, Calcagnotto A, Perrone CE, Richie JP
The Prostate, 2014; 74(16) : 1663-73 | PMID: 25250521

A methionine-restricted diet and endurance exercise decrease bone mass and extrinsic strength but increase intrinsic strength in growing male rats
Huang TH, Lewis JL, Lin HS, Kuo LT, Mao SW, Tai YS, Chang MS, Ables GP, Perrone CE, Yang RS
The Journal of Nutrition, 2014; 144(5) : 621-30 | PMID: 24647387

The First International Mini-Symposium on Methionine Restriction and Lifespan
Ables GP, Brown-Borg HM, Buffenstein R, Church CD, Elshorbagy AK, Gladyshev VN, Huang TH, Miller RA, Mitchell JR, Richie JP, Rogina B, Stipanuk MH, Orentreich DS, Orentreich N
Frontiers in Genetics, 2014; 5: 122 | PMID: 24847356

Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice
Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N
Metabolism: Clinical and Experimental, 2013; 62(11) : 1651-61 | PMID: 23928105

Metabolic adaptations to methionine restriction that benefit health and lifespan in rodents
Perrone CE, Malloy VL, Orentreich DS, Orentreich N
Experimental Gerontology, 2013; 48(7) : 654-60 | PMID: 22819757

Effect of taurine and N-acetylcysteine on methionine restriction-mediated adiposity resistance
Elshorbagy AK, Valdivia-Garcia M, Mattocks DA, Plummer JD, Orentreich DS, Orentreich N, Refsum H, Perrone CE
Metabolism: Clinical and Experimental, 2013; 62(4) : 509-17 | PMID: 23154184

Methionine-restricted C57BL/6J mice are resistant to diet-induced obesity and insulin resistance but have low bone density
Ables GP, Perrone CE, Orentreich D, Orentreich N
PloS One, 2012; 7(12) : e51357 | PMID: 23236485

Genomic and metabolic responses to methionine-restricted and methionine-restricted, cysteine-supplemented diets in Fischer 344 rat inguinal adipose tissue, liver and quadriceps muscle
Perrone CE, Mattocks DA, Plummer JD, Chittur SV, Mohney R, Vignola K, Orentreich DS, Orentreich N
Journal of Nutrigenetics and Nutrigenomics, 2012; 5(3) : 132-57 | PMID: 23052097

Update on pparγ and nonalcoholic Fatty liver disease
Ables GP
PPAR Research, 2012; 2012: 912351 | PMID: 22966224

Dietary methionine restriction increases fat oxidation in obese adults with metabolic syndrome
Plaisance EP, Greenway FL, Boudreau A, Hill KL, Johnson WD, Krajcik RA, Perrone CE, Orentreich N, Cefalu WT, Gettys TW
The Journal of Clinical Endocrinology and Metabolism, 2011; 96(5) : E836-40 | PMID: 21346062

Dietary glycine supplementation mimics lifespan extension by dietary methionine restriction in Fisher 344 rats.
Brind J, Malloy V, Augie I, Caliendo N, Vogelman JH, Zimmerman JA, Orentreich N.

FASEB Journal, 2011; (25) : 528.2 | PMID:

Circulating angiopoietins-1 and -2, angiopoietin receptor Tie-2 and vascular endothelial growth factor-A as biomarkers of acute myocardial infarction: a prospective nested case-control study
Iribarren C, Phelps BH, Darbinian JA, McCluskey ER, Quesenberry CP, Hytopoulos E, Vogelman JH, Orentreich N
BMC Cardiovascular Disorders, 2011; 11: 31 | PMID: 21672190

Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase
Elshorbagy AK, Valdivia-Garcia M, Mattocks DA, Plummer JD, Smith AD, Drevon CA, Refsum H, Perrone CE
Journal of Lipid Research, 2011; 52(1) : 104-12 | PMID: 20871132

Sulfur amino acids in methionine-restricted rats: hyperhomocysteinemia
Elshorbagy AK, Valdivia-Garcia M, Refsum H, Smith AD, Mattocks DA, Perrone CE
Nutrition (Burbank, Los Angeles County, Calif.), 2010; 26(11-12) : 1201-4 | PMID: 20080389

Dietary methionine restriction enhances metabolic flexibility and increases uncoupled respiration in both fed and fasted states
Hasek BE, Stewart LK, Henagan TM, Boudreau A, Lenard NR, Black C, Shin J, Huypens P, Malloy VL, Plaisance EP, Krajcik RA, Orentreich N, Gettys TW
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 2010; 299(3) : R728-39 | PMID: 20538896

Role of β-adrenergic receptors in the hyperphagic and hypermetabolic responses to dietary methionine restriction
Plaisance EP, Henagan TM, Echlin H, Boudreau A, Hill KL, Lenard NR, Hasek BE, Orentreich N, Gettys TW
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 2010; 299(3) : R740-50 | PMID: 20554934

Methionine restriction effects on mitochondrial biogenesis and aerobic capacity in white adipose tissue, liver, and skeletal muscle of F344 rats
Perrone CE, Mattocks DA, Jarvis-Morar M, Plummer JD, Orentreich N
Metabolism: Clinical and Experimental, 2010; 59(7) : 1000-11 | PMID: 20045141

Association of prediagnostic serum vitamin D levels with the development of basal cell carcinoma
Asgari MM, Tang J, Warton ME, Chren MM, Quesenberry CP, Bikle D, Horst RL, Orentreich N, Vogelman JH, Friedman GD
The Journal of Investigative Dermatology, 2010; 130(5) : 1438-43 | PMID: 20043012

Insulin-like growth factors, their binding proteins, and prostate cancer risk: analysis of individual patient data from 12 prospective studies
Roddam AW, Allen NE, Appleby P, Key TJ, Ferrucci L, Carter HB, Metter EJ, Chen C, Weiss NS, Fitzpatrick A, Hsing AW, Lacey JV, Helzlsouer K, Rinaldi S, Riboli E, Kaaks R, Janssen JA, Wildhagen MF, Schrӧder FH, Platz EA, Pollak M, Giovannucci E, Schaefer C, Quesenberry CP, Vogelman JH, Severi G, English DR, Giles GG, Stattin P, Hallmans G, Johansson M, Chan JM, Gann P, Oliver SE, Holly JM, Donovan J, Meyer F, Bairati I, Galan P
Annals of Internal Medicine, 2008; 149(7) : 461-71, W83-8 | PMID: 18838726

Helicobacter pylori infection and development of pancreatic cancer
de Martel C, Llosa AE, Friedman GD, Friedmana GD, Vogelman JH, Orentreich N, Stolzenberg-Solomon RZ, Parsonnet J
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2008; 17(5) : 1188-94 | PMID: 18483341

Endogenous sex hormones and prostate cancer: a collaborative analysis of 18 prospective studies
Endogenous Hormones and Prostate Cancer Collaborative Group, Roddam AW, Allen NE, Appleby P, Key TJ
Journal of the National Cancer Institute, 2008; 100(3) : 170-83 | PMID: 18230794

Methionine restriction effects on 11β-HSD1 activity and lipogenic/lipolytic balance in F344 rat adipose tissue
Perrone CE, Mattocks DA, Hristopoulos G, Plummer JD, Krajcik RA, Orentreich N
Journal of Lipid Research, 2008; 49(1) : 12-23 | PMID: 17909224

Transcriptional response to aging and caloric restriction in heart and adipose tissue
Linford NJ, Beyer RP, Gollahon K, Krajcik RA, Malloy VL, Demas V, Burmer GC, Rabinovitch PS
Aging Cell, 2007; 6(5) : 673-88 | PMID: 17874999

Serum ghrelin levels and risk of subsequent adenocarcinoma of the esophagus
de Martel C, Haggerty TD, Corley DA, Vogelman JH, Orentreich N, Parsonnet J
The American Journal of Gastroenterology, 2007; 102(6) : 1166-72 | PMID: 17378911

Infections and “unrelated” diseases
Orentreich N
Hawaii Medical Journal, 2006; 65(11) : 308-9 | PMID: 17265989

Methionine restriction decreases visceral fat mass and preserves insulin action in aging male Fischer 344 rats independent of energy restriction
Malloy VL, Krajcik RA, Bailey SJ, Hristopoulos G, Plummer JD, Orentreich N
Aging Cell, 2006; 5(4) : 305-14 | PMID: 16800846

Epstein-Barr virus and multiple sclerosis: evidence of association from a prospective study with long-term follow-up
DeLorenze GN, Munger KL, Lennette ET, Orentreich N, Vogelman JH, Ascherio A
Archives of Neurology, 2006; 63(6) : 839-44 | PMID: 16606758

Does the association between serum endostatin, an endogenous anti-angiogenic protein, and acute myocardial infarction differ by race?
Iribarren C, Herrinton LJ, Darbinian JA, Tamarkin L, Malinowski D, Vogelman JH, Orentreich N, Baer D
Vascular Medicine (London, England), 2006; 11(1) : 13-20 | PMID: 16669408

Helicobacter pylori infection and the risk of development of esophageal adenocarcinoma
de Martel C, Llosa AE, Farr SM, Friedman GD, Vogelman JH, Orentreich N, Corley DA, Parsonnet J
The Journal of Infectious Diseases, 2005; 191(5) : 761-7 | PMID: 15688293

Tissue glutathione and cysteine levels in methionine-restricted rats
Richie JP, Komninou D, Leutzinger Y, Kleinman W, Orentreich N, Malloy V, Zimmerman JA
Nutrition (Burbank, Los Angeles County, Calif.), 2004; 20(9) : 800-5 | PMID: 15325691

A prospective study of Chlamydia pneumoniae infection and risk of MS in two US cohorts
Munger KL, DeLorenze GN, Levin LI, Rubertone MV, Vogelman JH, Peck CA, Peeling RW, Orentreich N, Ascherio A
Neurology, 2004; 62(10) : 1799-803 | PMID: 15159481

Methionine restriction inhibits age-related spontaneous tumorigenesis in F344 rats.
Komninou D, Malloy V, Krajcik R, Rivenson A, Orentreich N, Zimmerman JA, Richie JP Jr

Proceedings of the American Association of Cancer Research, 2004; (45) : 3919 | PMID:

No association between serum levels of tumor necrosis factor-α (TNF-α) or the soluble receptors sTNFR1 and sTNFR2 and breast cancer risk
Krajcik RA, Massardo S, Orentreich N
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2003; 12(9) : 945-6 | PMID: 14504210

CagA status of Helicobacter pylori infection and p53 gene mutations in gastric adenocarcinoma (letter)
Shibata A, Parsonnet J, Longacre TA, Garcia MI, Puligandla B, Davis RE, Vogelman JH, Orentreich N, Habel LA

Carcinogenesis, 2003; 1(24) : 147 | PMID:

Transplants from balding and hairy androgenetic alopecia scalp regrow hair comparably well on immunodeficient mice
Krajcik RA, Vogelman JH, Malloy VL, Orentreich N
Journal of the American Academy of Dermatology, 2003; 48(5) : 752-9 | PMID: 12734505

C-reactive protein, Helicobacter pylori, Chlamydia pneumoniae, cytomegalovirus and risk for myocardial infarction
Witherell HL, Smith KL, Friedman GD, Ley C, Thom DH, Orentreich N, Vogelman JH, Parsonnet J
Annals of Epidemiology, 2003; 13(3) : 170-7 | PMID: 12604160

Nutritional control of aging
Zimmerman JA, Malloy V, Krajcik R, Orentreich N
Experimental Gerontology, 2003; 38(1-2) : 47-52 | PMID: 12543260

Insulin-like growth factor I (IGF-I), IGF-binding proteins, and breast cancer
Krajcik RA, Borofsky ND, Massardo S, Orentreich N
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2002; 11(12) : 1566-73 | PMID: 12496045

Utility of insulin-like growth factor-1 as a biomarker in epidemiologic studies
Borofsky ND, Vogelman JH, Krajcik RA, Orentreich N
Clinical Chemistry, 2002; 48(12) : 2248-51 | PMID: 12446484

CagA status of Helicobacter pylori infection and p53 gene mutations in gastric adenocarcinoma
Shibata A, Parsonnet J, Longacre TA, Garcia MI, Puligandla B, Davis RE, Vogelman JH, Orentreich N, Habel LA
Carcinogenesis, 2002; 23(3) : 419-24 | PMID: 11895856

Plasmagel®: A novel injectable autologous material for soft tissue augmentation.

Krajcik R, Orentreich DS, Orentreich N

Journal of Aesthetic Dermatology and Cosmetic Surgery, 1999; 1(2) : 109-15 | PMID:

Effect of supplementation with chromium picolinate on antibody titers to 5-hydroxymethyl uracil
Kato I, Vogelman JH, Dilman V, Karkoszka J, Frenkel K, Durr NP, Orentreich N, Toniolo P
European Journal of Epidemiology, 1998; 14(6) : 621-6 | PMID: 9794131

Gastrin and colorectal cancer: a prospective study
Thorburn CM, Friedman GD, Dickinson CJ, Vogelman JH, Orentreich N, Parsonnet J
Gastroenterology, 1998; 115(2) : 275-80 | PMID: 9679032

Novel delivery systems for coagulation proteins
Miekka SI, Jameson T, Singh M, Woolverton C, Lin HM, Krajcik R, MacPhee M, Drohan WN
Haemophilia : the Official Journal of the World Federation of Hemophilia, 1998; 4(4) : 436-42 | PMID: 9873772

Association between high-density lipoprotein cholesterol and breast cancer varies by menopausal status
Moorman PG, Hulka BS, Hiatt RA, Krieger N, Newman B, Vogelman JH, Orentreich N
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 1998; 7(6) : 483-8 | PMID: 9641492

Prediagnostic serum vitamin D and breast cancer
Hiatt RA, Krieger N, Lobaugh B, Drezner MK, Vogelman JH, Orentreich N
Journal of the National Cancer Institute, 1998; 90(6) : 461-3 | PMID: 9521171

IGF-I and prostate cancer.
Schaefer C, Friedman GD, Quesenberry CP Jr, Orentreich N, Vogelman JH

Science, 1998; 282(5387) : 199a | PMID:

Risk for gastric lymphoma in persons with CagA+ and CagA- Helicobacter pylori infection
Witherell HL, Hansen S, Jellum E, Orentreich N, Vogelman JH, Parsonnet J
The Journal of Infectious Diseases, 1997; 176(6) : 1641-4 | PMID: 9395383

Interaction between a semisynthetic diet and indole-3-carbinol on mammary tumor incidence in Balb/cfC3H mice
Malloy VL, Bradlow HL, Orentreich N
Anticancer Research, 1997; 17(6D) : 4333-7 | PMID: 9494529

Cortisol reduces hippocampal glucose metabolism in normal elderly, but not in Alzheimer’s disease
de Leon MJ, McRae T, Rusinek H, Convit A, De Santi S, Tarshish C, Golomb J, Volkow N, Daisley K, Orentreich N, McEwen B
The Journal of Clinical Endocrinology and Metabolism, 1997; 82(10) : 3251-9 | PMID: 9329348

Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection
Parsonnet J, Friedman GD, Orentreich N, Vogelman H
Gut, 1997; 40(3) : 297-301 | PMID: 9135515

In vitro IGFs and bFGF upregulate human hair follicles respectively through follicular stem cells and papilla cells.
Yang J, Agrawal P, Orentreich N

Journal of Investigative Dermatology, 1997; 108: 621 | PMID:

A non-invasive method for assessing antiandrogenic activity on the ear sebaceous gland of the Syrian golden hamster.
Brind J, Lemon LJ, Malloy VL, Orentreich N

Journal of Investigative Dermatology, 1997; 108: 655 | PMID:

5 α-reductase activity and prostate cancer: a case-control study using stored sera
Guess HA, Friedman GD, Sadler MC, Stanczyk FZ, Vogelman JH, Imperato-McGinley J, Lobo RA, Orentreich N
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 1997; 6(1) : 21-4 | PMID: 8993793

A simple, differential extraction method for the simultaneous direct radioimmunoassay of androgens and androgen glucuronides in human serum
Brind J, Borofsky N, Chervinsky K, Vogelman JH, Orentreich N
Steroids, 1996; 61(7) : 429-32 | PMID: 8837296

Spotlight on DHEA: a marker for progression of HIV infection?
Brind J
The Journal of Laboratory and Clinical Medicine, 1996; 127(6) : 522-3 | PMID: 8648255

Seasonal variation in vitamin D, vitamin D-binding protein, and dehydroepiandrosterone: risk of prostate cancer in black and white men
Corder EH, Friedman GD, Vogelman JH, Orentreich N
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 1995; 4(6) : 655-9 | PMID: 8547833

Prostate-specific antigen as predictor of prostate cancer in black men and white men
Whittemore AS, Lele C, Friedman GD, Stamey T, Vogelman JH, Orentreich N
Journal of the National Cancer Institute, 1995; 87(5) : 354-60 | PMID: 7531773

Methionine restriction increases blood glutathione and longevity in F344 rats
Richie JP, Leutzinger Y, Parthasarathy S, Malloy V, Orentreich N, Zimmerman JA
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology, 1994; 8(15) : 1302-7 | PMID: 8001743

Helicobacter pylori infection and gastric lymphoma
Parsonnet J, Hansen S, Rodriguez L, Gelb AB, Warnke RA, Jellum E, Orentreich N, Vogelman JH, Friedman GD
The New England Journal of Medicine, 1994; 330(18) : 1267-71 | PMID: 8145781

Breast cancer and serum organochlorines: a prospective study among white, black, and Asian women
Krieger N, Wolff MS, Hiatt RA, Rivera M, Vogelman J, Orentreich N
Journal of the National Cancer Institute, 1994; 86(8) : 589-99 | PMID: 8145274

Vitamin D and prostate cancer: a prediagnostic study with stored sera
Corder EH, Guess HA, Hulka BS, Friedman GD, Sadler M, Vollmer RT, Lobaugh B, Drezner MK, Vogelman JH, Orentreich N
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, ; 2(5) : 467-72 | PMID: 8220092

Helicobacter pylori, pepsinogen, and risk for gastric adenocarcinoma
Parsonnet J, Samloff IM, Nelson LM, Orentreich N, Vogelman JH, Friedman GD
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, ; 2(5) : 461-6 | PMID: 8220091

Senescent decline in serum dehydroepiandrosterone sulfate concentrations in a population of wild baboons
Sapolsky RM, Vogelman JH, Orentreich N, Altmann J
Journal of Gerontology, 1993; 48(5) : B196-200 | PMID: 8366259

Low methionine ingestion by rats extends life span
Orentreich N, Matias JR, DeFelice A, Zimmerman JA
The Journal of Nutrition, 1993; 123(2) : 269-74 | PMID: 8429371

Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men
Orentreich N, Brind JL, Vogelman JH, Andres R, Baldwin H
The Journal of Clinical Endocrinology and Metabolism, 1992; 75(4) : 1002-4 | PMID: 1400863

Relationship between the concentrations of estriol sulfate and estrone sulfate in human breast cyst fluid
Levitz M, Raju U, Arcuri F, Brind JL, Vogelman JH, Orentreich N, Granata OM, Castagnetta L
The Journal of Clinical Endocrinology and Metabolism, 1992; 75(3) : 726-9 | PMID: 1387652

Elevated serum dehydroepiandrosterone sulfate levels in practitioners of the Transcendental Meditation (TM) and TM-Sidhi programs
Glaser JL, Brind JL, Vogelman JH, Eisner MJ, Dillbeck MC, Wallace RK, Chopra D, Orentreich N
Journal of Behavioral Medicine, 1992; 15(4) : 327-41 | PMID: 1404349

The possibility of lidocaine ion pair absorption through excised hairless mouse skin
Nash RA, Mehta DB, Matias JR, Orentreich N
Skin Pharmacology : the Official Journal of the Skin Pharmacology Society, 1992; 5(3) : 160-70 | PMID: 1445706

Helicobacter pylori infection and the risk of gastric carcinoma
Parsonnet J, Friedman GD, Vandersteen DP, Chang Y, Vogelman JH, Orentreich N, Sibley RK
The New England Journal of Medicine, 1991; 325(16) : 1127-31 | PMID: 1891020

Epstein-Barr virus antibody patterns preceding the diagnosis of non-Hodgkin’s lymphoma
Mueller N, Mohar A, Evans A, Harris NL, Comstock GW, Jellum E, Magnus K, Orentreich N, Polk BF, Vogelman J
International Journal of Cancer. Journal International Du Cancer, 1991; 49(3) : 387-93 | PMID: 1655660

Direct radioimmunoassay of androstenediol-3-sulfate in the serum of normal men
Brind JL
Steroids, 1991; 56(6) : 320-4 | PMID: 1926228

Epstein-Barr virus antibody patterns preceding the diagnosis of nasopharyngeal carcinoma
Chan CK, Mueller N, Evans A, Harris NL, Comstock GW, Jellum E, Magnus K, Orentreich N, Polk BF, Vogelman J
Cancer Causes & Control : CCC, 1991; 2(2) : 125-31 | PMID: 1651778

The predictive value of serum β-carotene for subsequent development of lung cancer
Orentreich N, Matias JR, Vogelman JH, Salkeld RM, Bhagavan H, Friedman GD
Nutrition and Cancer, 1991; 16(3-4) : 167-9 | PMID: 1775382

Obese men have elevated plasma levels of estrone sulfate
Brind J, Strain G, Miller L, Zumoff B, Vogelman J, Orentreich N
International Journal of Obesity, 1990; 14(6) : 483-6 | PMID: 2401584

Radioimmunoassay of estrone sulfate in the serum of normal men after a non-chromatographic procedure that eliminates interference from dehydroepiandrosterone sulfate
Brind JL, Chervinsky K, Vӧlgelman JH, Orentreich N
Steroids, 1990; 55(1) : 32-5 | PMID: 2137944

Studies on the efficacy of methyl esters of n-alkyl fatty acids as penetration enhancers
Chukwumerije O, Nash RA, Matias JR, Orentreich N
The Journal of Investigative Dermatology, 1989; 93(3) : 349-52 | PMID: 2768835

Radioimmunoassay of estrone sulfate in the serum of normal men after a chromatographic procedure that eliminates dehydroepiandrosterone sulfate interference
Brind JL, Chervinsky K, Vogelman JH, Orentreich N
Steroids, 1989; 54(1) : 21-35 | PMID: 2530662

Hodgkin’s disease and Epstein-Barr virus. Altered antibody pattern before diagnosis
Mueller N, Evans A, Harris NL, Comstock GW, Jellum E, Magnus K, Orentreich N, Polk BF, Vogelman J
The New England Journal of Medicine, 1989; 320(11) : 689-95 | PMID: 2537928

Animal models of androgen-dependent disorders of the pilosebaceous apparatus. 1. The androchronogenetic alopecia (AGA) mouse as a model for male-pattern baldness
Matias JR, Malloy V, Orentreich N
Archives of Dermatological Research, 1989; 281(4) : 247-53 | PMID: 2774656

A new reversed phase, paired ion thin-layer chromatographic method for steroid sulfate separations
Brind JL, Kuo SW, Chervinsky K, Orentreich N
Steroids, ; 52(5-6) : 561-70 | PMID: 2978281

Synergistic antiandrogenic effects of topical combinations of 5 α-reductase and androgen receptor inhibitors in the hamster sebaceous glands
Matias JR, Malloy VL, Orentreich N
The Journal of Investigative Dermatology, 1988; 91(5) : 429-33 | PMID: 3171218

The effect of testosterone, cyproterone acetate, and minoxidil on hair loss in the androchronogenetic alopecia mouse
Matias JR, Orentreich N
Clinics in Dermatology, ; 6(4) : 169-76 | PMID: 3214819

Effects of toxic shock syndrome Staphylococcus aureus, endotoxin and tampons in a mouse model
Tierno PM, Malloy V, Matias JR, Hanna BA
Clinical and Investigative Medicine. Médecine Clinique Et Experimentale, 1987; 10(2) : 64-70 | PMID: 3581548

Serum retinol and retinol-binding protein levels do not predict subsequent lung cancer
Friedman GD, Blaner WS, Goodman DS, Vogelman JH, Brind JL, Hoover R, Fireman BH, Orentreich N
American Journal of Epidemiology, 1986; 123(5) : 781-9 | PMID: 3962962

Analysis of ear sebum of the Syrian hamster (Mesocricetus auratus) reveals pronounced sexual dimorphism
Brind JL, Alani E, Wheatley VR, Orentreich N
Comparative Biochemistry and Physiology. B, Comparative Biochemistry, 1986; 84(3) : 403-7 | PMID: 3743033

A new partition thin-layer chromatographic method for steroid separations
Brind JL, Kuo SW, Chervinsky K, Fitzgerald K, Orentreich N
Steroids, 1985; 45(6) : 565-71 | PMID: 3835732

Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood
Orentreich N, Brind JL, Rizer RL, Vogelman JH
The Journal of Clinical Endocrinology and Metabolism, 1984; 59(3) : 551-5 | PMID: 6235241

In vitro testosterone metabolism in the mouse preputial gland: intercellular co-operation and changes with cell maturation
Brind JL, Marinescu D, Gomez EC, Wheatley VR, Orenteich N
The Journal of Endocrinology, 1984; 100(3) : 377-88 | PMID: 6699537

The local antiandrogenic effect of the intracutaneous injection of progesterone in the flank organ of sexually mature male Syrian golden hamster
Orentreich N, Matias JR, Malloy V
Archives of Dermatological Research, 1984; 276(6) : 401-5 | PMID: 6517612

The lack of effect of 11 α-hydroxyprogesterone on the flank-organ and ear sebaceous glands of adult male Syrian golden hamsters
Matias JR, Orentreich N, Malloy V, De Feo CP, Matias L
Archives of Dermatological Research, 1984; 276(5) : 346-8 | PMID: 6486882

The hamster ear sebaceous glands. I. Examination of the regional variation by stripped skin planimetry
Matias JR, Orentreich N
The Journal of Investigative Dermatology, 1983; 81(1) : 43-6 | PMID: 6863979

Stimulation of hamster sebaceous glands by epidermal growth factor
Matias JR, Orentreich N
The Journal of Investigative Dermatology, 1983; 80(6) : 516-9 | PMID: 6602188

Reversible stage-specific embryonic inhibition mediated by the presence of adults in the annual fish Nothobranchius guentheri
Inglima K, Perlmutter A, Markofsky J
The Journal of Experimental Zoology, 1981; 215(1) : 23-33 | PMID: 7229598

The effect of aging on the rate of linear nail growth
Orentreich N, Markofsky J, Vogelman JH
The Journal of Investigative Dermatology, 1979; 73(1) : 126-30 | PMID: 448171

Body water compartments with human aging using fat-free mass as the reference standard
Lesser GT, Markofsky J
The American Journal of Physiology, 1979; 236(3) : R215-20 | PMID: 426098

Histopathological observations of the kidney during aging of the male annual fish Nothobranchius guentheri
Markofsky J, Milstoc M
Experimental Gerontology, 1979; 14(3) : 149-55 | PMID: 456446

Aging changes in the liver of the male annual cyprinodont fish, Nothobranchius guentheri
Markofsky J, Milstoc M
Experimental Gerontology, 1979; 14(1) : 11-20 | PMID: 456435

Black-hair follicular dysplasia in dogs
Selmanowitz VJ, Markofsky J, Orentreich N
Journal of the American Veterinary Medical Association, 1977; 171(10) : 1079-81 | PMID: 591423

Cutaneous changes associated with aging
Selmanowitz VJ
The Journal of Dermatologic Surgery and Oncology, 1977; 3(6) : 628-34 | PMID: 591670

Heritability of an ectodermal defect. A study of affected dogs
Selmanowitz VJ, Markofsky J, Orentreich N
The Journal of Dermatologic Surgery and Oncology, 1977; 3(6) : 623-6 | PMID: 579352

The effects of temperature and season of collection on the onset and duration of diapause in embryos of the annual fish Nothobranchius guentheri
Markofsky J, Matias JR
The Journal of Experimental Zoology, 1977; 202(1) : 49-56 | PMID: 925663

An improved method for repeated plasmapheresis in the rat
Markofsky J, Orentreich N
Laboratory Animal Science, 1976; 26(1) : 93-5 | PMID: 1263434

Longitudinal and cross-sectional observations of growth and body composition with age in laboratory populations of the male annual cyprinodont fish, Nothobranchius guentheri
Markofsky J
Experimental Gerontology, 1976; 11(5-6) : 171-7 | PMID: 1021418

Lentiginosis profusa syndrome. IV. Giant pigment granules (light microscopy)
Selmanowitz VJ
Acta Dermato-venereologica, 1975; 55(6) : 481-4 | PMID: 55042

Aging and the passage of L-tyrosine, L-DOPA, and inulin into mouse brain slices in vitro
Finch CE, Jonec V, Hody G, Walker JP, Morton-Smith W, Alper A, Dougher GJ
Journal of Gerontology, 1975; 30(1) : 33-40 | PMID: 1109390

Fingerprint arches in alopecia areata
Selmanowitz VJ, Victor S, Warburton D, Orentreich N
Archives of Dermatology, 1974; 110(4) : 570-1 | PMID: 4413474

Proceedings: Mammogenesis in transsexuals
Orentreich N, Durr NP
The Journal of Investigative Dermatology, 1974; 63(1) : 142-6 | PMID: 4365991

Enlarged seminal vesicles of senescent C57BL-6J mice
Finch CE, Girgis FG
Journal of Gerontology, 1974; 29(2) : 134-8 | PMID: 4811948

Hematologic and serum electrolyte values of the C57BL-6J male mouse in maturity and senescence
Finch CE, Foster JR
Laboratory Animal Science, 1973; 23(3) : 339-49 | PMID: 4351468

Growth differences in subgroups of varying longevities in a laboratory population of the male annual cyprinodont fish, Nothobranchius guentheri (Peters)
Markofsky J, Perlmutter A
Experimental Gerontology, 1973; 8(2) : 65-73 | PMID: 4696516

Age at sexual maturity and its relationship to longevity in the male annual cyprinodont fish, Nothobranchius guentheri
Markofsky J, Perlmutter A
Experimental Gerontology, 1972; 7(2) : 131-5 | PMID: 5042930

Canine hereditary black hair follicular dysplasia
Selmanowitz VJ, Kramer KM, Orentreich N
The Journal of Heredity, 1972; 63(1) : 43-4 | PMID: 5019544

Lentiginosis profusa syndrome (multiple lentigines syndrome)
Selmanowitz VJ, Orentreich N, Felsenstein JM
Archives of Dermatology, 1971; 104(4) : 393-401 | PMID: 5000391

Disorders of the hair and scalp in childhood
Orentreich N
Pediatric Clinics of North America, 1971; 18(3) : 953-74 | PMID: 5569747

Ectodermal dysplasias in cattle. Analogues in man
Selmanowitz VJ
The British Journal of Dermatology, 1971; 84(3) : 258-65 | PMID: 4929446

Cosmetic improvement of factitial defects
Orentreich N, Selmanowitz VJ
Medical Trial Technique Quarterly, 1970; 17(2) : 172-80 | PMID: 4250223

Multiple noduli cutanei and urinary tract abnormalities. A possible significant association
Selmanowitz VJ, Lerer WN, Orentreich N
Cancer, 1970; 26(6) : 1256-60 | PMID: 5483657

Congenital ectodermal defect in miniature poodles
Selmanowitz VJ, Kramer KM, Orentreich N
The Journal of Heredity, 1970; 61(5) : 196-9 | PMID: 5519670

Uniovular twins discordant for cutaneous mastocytosis
Selmanowitz VJ, Orentreich N, Tiangco CC, Demis J
Archives of Dermatology, 1970; 102(1) : 34-41 | PMID: 4250565

Mastocytosis. A clinical genetic evaluation
Selmanowitz VJ, Orentreich N
The Journal of Heredity, 1970; 61(3) : 91-4 | PMID: 5424687

Congenital ectodermal dysplasia in male miniature poodle siblings
Selmanowitz VJ, Kramer KM, Orentreich N, Hyman AB
Archives of Dermatology, 1970; 101(5) : 613-5 | PMID: 5462764

A method for the intensive repeated plasmapheresis of the rat
Rizer RL, Shaw LG, Orentreich N
Laboratory Animal Care, 1970; 20(1) : 105-6 | PMID: 4244714

Effect of plasmapheresis on nephrectomized dogs
Hausman MS, Hotchkiss RS, Orentreich N
Investigative Urology, 1967; 5(3) : 276-87 | PMID: 6073636