Sailendra Nichenametla Recipient of Inaugural Hevolution/AFAR New Investigator Award in Aging Biology and Geroscience
Senior Scientist Sailendra Nichenametla, Ph.D., has been named as a recipient of the inaugural Hevolution/AFAR New Investigator Awards in Aging Biology and Geroscience Research, presented by the American Federation for Aging Research (AFAR) and Hevolution Foundation. The US$375,000 award supports research projects in basic biology of aging or geroscience—a research paradigm based on addressing the biology of aging and age-related disease to promote healthy aging. Dr. Nichenametla will utilize the funds to investigate the role of serinogenesis in regulating lipid metabolism.
Serine Supplementation Could Mitigate Cognitive Impairments of an Aging Hypothalamus
Age-related decline in menin has led researchers to consider its role in the context of aging. Their findings revealed that decreasing menin in younger mice resulted in elevated hypothalamic neuroinflammation and several aging-related characteristics such as decreased bone mass and skin thickness, cognitive decline, and a slightly reduced lifespan.
Can Ultrasound Therapy Delay Aging?
Researchers from the University of Texas have provided preliminary evidence for a mechanical method to reduce the burden of senescent cells utilizing a low-cost, non-invasive application of low-frequency ultrasound therapy.
New Study Supports the “Information Theory of Aging” and Its Potential to Combat Aging
A new study describes both the importance of maintaining epigenetic fidelity and a means to reverse the loss of epigenetic information.
Intermittent Fasting Shown to Effectively Treat Type 2 Diabetes
A recent study published in The Journal of Clinical Endocrinology & Metabolism has shown a dietary approach that might reverse type 2 diabetes for millions of people currently suffering from this disease. Moreover, this approach costs nothing and does not require...
A Modified Mediterranean Diet Reduces Unhealthy Visceral Fat
There is ever-growing evidence that achieving a healthy diet and healthy amounts of body fat are more nuanced than simply accounting for calories or body fat percentage. Recent research has found that polyphenols, contained in plants, likely contribute to the health benefits provided by a healthy diet, specifically aiding in reduction of unhealthy visceral fat.
2022 OFAS Report of Directors
As the year comes to a close, we at the Orentreich Foundation for the Advancement of Science (OFAS) wish to thank our friends around the globe for their continued support. The 2022 Report of the Director is available for download.
Cellular Reprogramming, a Viable Means of Lifespan Extension
A single short interval of cellular reprogramming can provide a robust and lasting systemic improvement to both the rate of aging and the function in numerous tissues.
A Bunch of Grapes a Day Might Keep the Doctor Away
Nutrition is vital to maintaining health and promoting longevity. The consumption of grapes has long been thought to impart health benefits, and numerous studies have attempted to uncover the phytochemicals responsible for this; however, the search for one or more specific molecules responsible for the putative benefits of dietary grapes has remained elusive. A recent study focuses on the consumption of whole grapes, providing evidence that dietary supplementation with grapes has the potential to improve the quality and duration of life.
Key Feature of Ant Longevity Revealed
In an attempt to understand secrets of longevity, researchers are focusing on the peculiar lifespan of ants, specifically queen ants. The typical lifespan of a worker ant is a modest 1 to 2 years; queen ants, however, can live up to 30 times longer. New research reveals the mechanism responsible for this extreme lifespan extension.
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