Naked mole-rats, peculiar-looking creatures that live in underground colonies, have fascinated scientists for years. How do naked mole-rats stay youthful and healthy for so long? In this article, we delve into the unique nature of these creatures, exploring the latest research that may unlock the secrets behind their extraordinary longevity and resilience.
Dr. Nichenametla’s lab is hiring a Senior Technician or a Senior Post-doctoral Fellow. The candidate will work on various SAAR-related projects associated with mechanisms, nutritional aspects, and prevention of diseases, including metabolic diseases, cancers, and proteostatic disorders. Responsibilities include generating data extensively from rodent models and occasionally from in vitro studies and clinical study specimens. Routine daily activities include performing experiments and data analysis, drafting publication-quality manuscripts, assisting in submitting grant proposals, and presenting work at scientific meetings. For more information, click here
A recent investigation into the molecular mechanisms underlying animal aging provides insights into potential preventive measures. The findings reveal a novel aspect of aging, characterized by an age-related escalation in the pace at which DNA is transformed into RNA and its impact on subsequently translated functional proteins.
Despite the challenges posed by the modern world’s food abundance and its negative impact on health and lifespan, intriguing research has emerged that harnesses the very sensation of hunger in an attempt to extend both.
Previous studies have demonstrated that hypoxia delays the senescence of cultured cells and extends the lifespan of simple organisms such as yeast, nematodes, and fruit flies. An intriguing new study by Harvard University researchers expands on these findings.
Sailendra Nichenametla Recipient of Inaugural Hevolution/AFAR New Investigator Award in Aging Biology and Geroscience
Senior Scientist Sailendra Nichenametla, Ph.D., has been named as a recipient of the inaugural Hevolution/AFAR New Investigator Awards in Aging Biology and Geroscience Research, presented by the American Federation for Aging Research (AFAR) and Hevolution Foundation. The US$375,000 award supports research projects in basic biology of aging or geroscience—a research paradigm based on addressing the biology of aging and age-related disease to promote healthy aging. Dr. Nichenametla will utilize the funds to investigate the role of serinogenesis in regulating lipid metabolism.
Age-related decline in menin has led researchers to consider its role in the context of aging. Their findings revealed that decreasing menin in younger mice resulted in elevated hypothalamic neuroinflammation and several aging-related characteristics such as decreased bone mass and skin thickness, cognitive decline, and a slightly reduced lifespan.
Researchers from the University of Texas have provided preliminary evidence for a mechanical method to reduce the burden of senescent cells utilizing a low-cost, non-invasive application of low-frequency ultrasound therapy.
A new study describes both the importance of maintaining epigenetic fidelity and a means to reverse the loss of epigenetic information.
A recent study published in The Journal of Clinical Endocrinology & Metabolism has shown a dietary approach that might reverse type 2 diabetes for millions of people currently suffering from this disease. Moreover, this approach costs nothing and does not require...
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