Weight Loss and Concomitant Adipose Autophagy in Methionine-Restricted Obese Mice is Not Dependent on Adiponectin or FGF21
Methionine restriction (MR) prevents obesity because of a futile lipid cycle in which two metabolic pathways run simultaneously in opposite directions and have no overall effect other than to dissipate energy in the form of heat. In this study, we show that MR...
The dietary switch that may boost longevity and its correlation to SAAR
A new epidemiological study published in The BMJ explores the association between eating red meat and the risk of death, specifically how risk of death can be lessened through dietary change—decreasing red meat consumption while increasing intake of healthier animal...
In Memoriam Norman Orentreich, MD
Dr. Norman Orentreich1922-2019 It is with profound sadness that we announce the recent passing of our Founder and Co-Director, Dr. Norman Orentreich. Dr. O, as he was known to staff, was a visionary and a charismatic leader who brought a remarkable passion and energy...
The EAT–Lancet Commission on Diet, Healthspan, and Sustainability
Human health, diet, and environmental sustainability are prevailing concerns that share many common uncertainties. Fulfilling the nutritional needs of a growing population while limiting environmental degradation is a critical challenge that requires global...
2018 OFAS Report of Directors
As we begin the new year, we at the Orentreich Foundation for the Advancement of Science (OFAS) are reminded of how grateful we are for our friends around the globe. We are pleased with the advances in our research this past year and for the...
OFAS Successfully Hosted AGA Session
This year, OFAS hosted a pre-meeting session at the AGE 47th Annual Meeting in Philadelphia. The theme of the conference was “Improving Resiliency to Delay Aging”, and the OFAS-sponsored session was focused on Nutrition and Longevity. The panel of speakers included:...
Analysis of environmental data strengthens the case for plant-based diets
Researchers at Oxford University and the Swiss agricultural research institute, Agroscope, have created the most comprehensive database on the environmental impacts of nearly 40,000 farms and 1,600 processors, packaging types, and retailers. This allows them to assess...
OFAS Hosting Session at AGE 47th Annual Meeting
For years, Orentreich Foundation for the Advancement of Science has researched biomedical interventions to prevent, halt, or reverse those disorders that decrease the quality or length of life. Our groundbreaking research on dietary methionine restriction has shown...
OFAS Will Lead Their First Jane’s Walk
The Orentreich Foundation for the Advancement of Science is excited to announce that we will be leading our first Jane’s Walk in New York City this year. For those who do not know, Jane’s Walk is an event inspired by Jane Jacobs, an activist who greatly influenced...
How Mindfulness Protects You as You Get Older
In our minds, old age is often associated with negative outcomes, such as a decline in physical health, but research consistently finds that older adults tend to experience more positive emotion than their younger counterparts. In this study, older adults reported...