The OFAS Team

Norman Orentreich, MD, FACP

Norman Orentreich, MD, FACP

Founder and Co-Director

Norman Orentreich, in six decades of dedication to medicine and related sciences, has always been on the cutting edge of discoveries and innovations in dermatology and cosmetic surgery. He pioneered hair transplant surgery; was the first President of the American Society for Dermatologic Surgery; was Clinical Professor in the New York University School of Medicine Department of Dermatology; and advised numerous medical facilities. He created and developed procedures and treatments for skin, hair, and nail maintenance, and also invented and patented medicines and medical devices for rejuvenating scarred and aging skin. Together with his son and partner Dr. David Orentreich, he has lectured internationally on procedures developed at the Orentreich Medical Group and on research at OFAS, and has written hundreds of articles and book chapters for medical textbooks and journals. In 1961 Dr. Orentreich founded OFAS. His early work sought to build upon the wound healing and aging studies of Alexis Carrell. Under Dr. Orentreich’s guidance, research at OFAS expanded to encompass aging, cancer, dermatology, and serum biomarkers, resulting in an extensive list of papers in peer-reviewed publications.
David Orentreich, MD

David Orentreich, MD

Co-Director

David Orentreich received his MD from Columbia College of Physicians and Surgeons in 1980 and has been a board-certified dermatologist practicing with the Orentreich Medical Group (OMG) since 1984. In addition to his daily clinical work, Dr. Orentreich is an Assistant Clinical Professor in the Department of Dermatology of the Ichan School of Medicine at Mt. Sinai, where he completed his own dermatology residency. He lectures nationally and internationally on current medical and surgical procedures in development at OMG. He is also closely involved in projects at OFAS, regularly attending meetings with scientific staff to oversee research. As a partner at OMG and Co-Director of OFAS, he has helped to create and develop numerous therapeutic procedures and maintenance treatments for the skin, hair, and nails, and has developed medicines and medical devices for the rejuvenation of scarred and aging skin. He has been Clinique Laboratories’ guiding dermatologist since 1987.
Bernardita Calinao, PhD

Bernardita Calinao, PhD

Deputy Director

Dr. Calinao holds a doctoral degree in Environmental Planning from the State University of New York College of Environmental Science and Forestry. She has over a decade of experience as the executive head of operations responsible for day-to-day leadership and management of financial, legal, research, safety, and regulatory concerns; overseeing external relations; strategic planning; and contract negotiation. Dr. Calinao also has more than fifteen years of environmental planning experience in the US and abroad, and has successfully directed more than 25 multidisciplinary environmental studies for engineering projects in the transportation and energy sectors.
Gene P. Ables, PhD

Gene P. Ables, PhD

Associate Science Director

Dr. Ables received his degree of Doctor of Veterinary Medicine from the University of the Philippines. He then obtained his PhD from Hokkaido University (Japan). His post-doctoral research in Preventive Medicine and Nutrition at Columbia University focused on liver lipid metabolism. In 2006, he was appointed Associate Research Scientist at the Columbia University Medical Center. Dr. Ables joined OFAS in April 2011 as a Senior Scientist. Recently appointed Associate Science Director, he leads staff in investigations of the methionine-restricted diet’s effects on metabolism, cancer, and epigenetics.
Jay E. Johnson, PhD

Jay E. Johnson, PhD

Senior Scientist

Dr. Johnson received his doctorate in Molecular Biology from Case Western Reserve University (Cleveland, OH). His post-doctoral work at Fox Chase Cancer Center (Philadelphia, PA) used a liposarcoma model system to investigate the maintenance of telomeres, important nucleoprotein structures with roles in aging and cancer. Dr. Johnson then joined the University of Pennsylvania (Philadelphia), where his early work explored cellular defects in patients with Werner and Bloom’s syndromes, genetic diseases characterized by accelerated aging and cancer predisposition. Dr. Johnson’s recent work has focused on exploring the mechanistic basis of the benefits of methionine restriction in S. cerevisiae and cultured mouse and human cells.

Sailendra N. Nichenametla, PhD

Sailendra N. Nichenametla, PhD

Senior Scientist

Dr. Nichenametla received his PhD in Integrative Biosciences from Pennsylvania State University (Hershey, PA) under OFAS consultant Dr. John Richie. He studies how genetics and the environment—diet, in particular—shape health. During graduate and postgraduate training, he investigated how bioactive compounds in milk, berries, and dietary fiber can affect diseases such as colon cancer and metabolic syndrome. While training for his PhD, he investigated how genetic variation in humans alters an individual’s capacity to combat oxidative stress and risk for cancers. He is currently studying biochemical and molecular mechanisms that lead to lifespan extension and other benefits induced by methionine restriction.

Consultants

Arthur J.L. Cooper, PhD Professor of Biochemistry and Molecular Biology, New York Medical College PhD, Weill Medical College of Cornell University Research interests include amino acid, sulfur, and energy metabolism; vitamin B6-containing enzymes; bioactivation (toxification) mechanisms; transglutaminases (protein cross linking enzymes); and neurodegenerative diseases.

Mark C. Horowitz, PhD Professor of Orthopaedics and Rehabilitation; Vice Chair for Research Education & Training, Yale University School of Medicine PhD, SUNY Upstate Medical Center Research interests include osteoimmunology; osteoblasts; osteoclasts; adipocytes; bone remodeling; mesenchymal stem cell differentiation; B cell transcription factors and bone

Sulli J. Popilskis, DVM Asst Professor of Clinical Anesthesiology and Physiology, New York Medical College DVM, Lithuanian Veterinary Academy

John P. Richie, PhD Professor of Public Health Sciences & Pharmacology, Penn State University College of Medicine PhD, University of Louisville Research interests include cancer risk in individuals and in populations; aging, nutrition, tobacco, and race/ethnicity as regulators or determinants of cancer risk.

Jay A. Zimmerman, PhD Adjunct Professor, St. John’s University PhD, Rutgers University Research interests include experimental gerontology; nutritional aspects of lifespan extension.